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Crescent Pharma Modafinil is a widely distributed, MHRA-authorised generic wakefulness-promoting medicine produced by Crescent Pharma Limited. Formulated to target central excessive daytime sleepiness associated with narcolepsy, Crescent Modafinil provides full bioequivalence and active ingredient parity with brand-name Provigil, serving as a trusted, cost-effective formulation across the UK National Health Service (NHS).
Crescent Pharma Limited (Basingstoke, UK)
100mg / 200mg (Modafinil Active Ingredient)
30 Tablets Per Box (Blister Strips)
Prescription-Only Medicine (POM) / Class C Controlled
Crescent Pharma Modafinil delivers identical pharmacokinetic profiles to the innovator medicine while adhering to strict UK MHRA manufacturing parameters. Below are the key chemical specifications, inactive excipient profiles, and clinical considerations.
Each Crescent Modafinil 100mg tablet contains exactly 113.5 mg of lactose monohydrate as a primary binding excipient. Additional inactive ingredients include microcrystalline cellulose, pregelatinized starch, croscarmellose sodium, povidone, and magnesium stearate. Patients with hereditary galactose intolerance, total lactase deficiency, or glucose-galactose malabsorption should review this profile with a clinician prior to starting therapy.
Crescent Modafinil acts as a central nervous system wakefulness-promoting agent. It binds to dopamine transporters (DAT) to inhibit dopamine reuptake, indirectly elevating extracellular levels of hypocretin, histamine, and norepinephrine in the hypothalamus. This mechanism promotes sustained alertness with significantly less risk of severe peripheral sympathetic stimulation compared to traditional amphetamine compounds.
Modafinil undergoes extensive hepatic metabolism, primary via CYP3A4/5 enzyme pathways. Modafinil acts as a CYP3A4 inducer, accelerating the breakdown of synthetic estrogens and progestogens. This reduces the efficacy of oral contraceptive pills, patches, implants, and vaginal rings. Alternative non-hormonal contraception must be maintained during treatment and for two full months after stopping the medication.
Crescent Pharma Modafinil is authorized by the UK MHRA under Marketing Authorisation licenses held by Crescent Pharma Limited. Produced in Good Manufacturing Practice (GMP) certified facilities, each batch undergoes strict release testing for purity, dissolution rate, and active ingredient stability.
Founded in 2003 in Hampshire, Crescent Pharma has grown into one of the largest independent generic pharmaceutical suppliers in the United Kingdom. Operating from its headquarters in Basingstoke alongside nationwide warehousing in Andover and South Yorkshire, Crescent supplies over 200 million medicine packs every year.
Crescent Pharma is an established partner to the National Health Service (NHS), hospital trusts, and retail pharmacy chains. By holding over 850 active UK Marketing Authorisations, Crescent maintains a reliable domestic supply chain that helps prevent drug shortages across critical therapeutic categories, including neurology and sleep medicine.
Every batch of Crescent Modafinil distributed across the UK undergoes comprehensive quality assurance auditing. Crescent’s dedicated UK pharmacovigilance team monitors post-market product safety, ensuring full compliance with MHRA safety updates, patient information guidelines, and clinical reporting standards. Modafinil UK helps you stay informed about the latest guidelines, safety recommendations, and regulatory updates in one trusted place.
Our commitment to quality and compliance ensures reliable services. Here is the process to get our services:
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Invoice
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Payment
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Delivery
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67 Southall Ave, Brighton and Hove, Brighton BN2 4GB, UK
+447462217141
contact@modafinil-uk.org
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Hi, I’m Matthew Young, a medical writer and editor based in the United Kingdom. I’m currently researching modafinil medicines, including Provigil, Milpharm Modafinil, Teva Modafinil, Accord Healthcare Modafinil, Brown & Burk UK Modafinil, Generic Modafinil and other brands, with a focus on medicine identification, regulatory guidance, product quality, safe usage, patient safety, and so on. My work combines medical literature, manufacturer information, and UK healthcare guidance to produce accurate, evidence-based articles that are easy to understand.
