Milpharm (Modafinil)

Milpharm Modafinil is a widely recognized, UK-licensed generic formulation of modafinil prescribed to treat severe excessive daytime sleepiness. Manufactured and distributed by Milpharm Limited, a UK-based subsidiary of Aurobindo Pharma, this medication offers a bioequivalent alternative to the reference listed drug, adhering strictly to the stringent regulatory standards of the UK Medicines and Healthcare products Regulatory Agency (MHRA).

Year Milpharm Was Acquired by the Global Aurobindo Pharma Group.

2000

International Markets Served by Parent Manufacturer Aurobindo.

100 +

More than 35 years of rich pharmaceutical founding history.

1950

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Manufacturer

Milpharm Limited (Aurobindo)

Strength

100mg / 200mg (Modafinil Active Ingredient)

Quantity

30 Tablets Per Box (Standard Blister Pack)

Regulatory Status

Prescription-Only Medicine (POM)

What is the Pharmacological Profile & Specifications of Milharm Modafinil?

Milpharm Modafinil is a chemically equivalent formulation to the original reference drug, acting centrally as a wakefulness-promoting agent. Below are the specific pharmaceutical properties, metabolic characteristics, and regulatory identifiers unique to this brand.

1. Inactive Ingredients & Specific Excipient Warnings

Patients must be aware of Milpharm’s specific inactive binding agents. Each Milpharm 100mg tablet contains exactly 113.500 mg of lactose monohydrate. Patients with rare hereditary problems of galactose intolerance, total lactase deficiency, or glucose-galactose malabsorption should consider this specific excipient profile before initiating therapy.

2. Pharmacodynamics & Target Receptors

While the exact mechanism remains fully undocumented, Milpharm’s formulation has been shown to bind directly to the dopamine transporter, subsequently inhibiting dopamine reuptake. Unlike classic psychomotor stimulants (such as amphetamines), it predominantly affects the specific brain regions implicated in regulating arousal, sleep, and vigilance without stimulating widespread systemic neuronal activation.

3. Metabolic Clearance & Enzyme Interactions

Milpharm Modafinil interacts significantly with hepatic cytochrome P450 pathways. It is known to induce CYP3A4/5 enzymes, which can drastically reduce the effectiveness of steroidal contraceptives (like the combined oral pill or implants) during treatment and for two months following cessation. Conversely, it may inhibit CYP2C19, potentially requiring dosage adjustments for patients concurrently taking SSRIs or tricyclic antidepressants.

4. UK MHRA Regulatory Registration

The 100mg formulation of Milpharm Modafinil is officially registered under the UK Product Licence PL 16363/0302. The Marketing Authorisation Holder is legally registered to Milpharm Limited, operating out of Stockley Park, Uxbridge, UK. This identifier guarantees the product has been legally audited for efficacy, safety, and GMP compliance within the United Kingdom.

More About Milpharm Limited

Brand History

The Aurobindo Pharma Connection

Milpharm Limited operates as the primary United Kingdom subsidiary for Aurobindo Pharma, one of the most prominent multinational pharmaceutical manufacturing companies in the world. By leveraging Aurobindo’s massive global supply chain and active pharmaceutical ingredient (API) production capabilities, Milpharm provides high-quality, bioequivalent medications at a more accessible cost to health services.

UK Distribution & Safety Oversight

Headquartered in Uxbridge, London (previously South Ruislip), Milpharm oversees the distribution and pharmacovigilance of its modafinil formulations strictly within the UK. The company operates under direct scrutiny of the MHRA, ensuring that every blister pack distributed to British pharmacies meets exact purity, stability, and chemical composition standards equal to the reference listed drug.

Trusted NHS Prescribing Presence

Within the UK healthcare system, Milpharm Modafinil is a standard dispensing option. It is prescribed across the NHS—initiated by specialist sleep clinics for narcolepsy, and sometimes off-label for severe fatigue in Multiple Sclerosis (MS) under strict shared-care prescribing guidelines between specialists and primary care general practitioners. If you want to get modafinil online via your prescription, please always go for approved companies like Milpharm.

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Location

67 Southall Ave, Brighton and Hove, Brighton BN2 4GB, UK

+447462217141

Email us

contact@modafinil-uk.org

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Frequently Asked Questions

Everything you need to know about Diazepam for Sale.

Is Milpharm Modafinil bioequivalent to brand-name Provigil?

Yes. Milpharm Modafinil is a licensed bioequivalent generic formulation authorized by the UK Medicines and Healthcare products Regulatory Agency (MHRA). It contains the identical active pharmaceutical ingredient (modafinil) at the same strengths (100mg and 200mg) and achieves equivalent rate and extent of systemic absorption as the innovator reference drug, Provigil.

What visual markings identify genuine Milpharm Modafinil tablets?

A: Milpharm Modafinil 100mg tablets are capsule-shaped, white to off-white uncoated tablets debossed with “41” on one side and “J” on the reverse side. The 200mg strength features specific registered numerical debossing under its unique MHRA Product Licence (PL 16363/0302). Genuine packaging always displays the manufacturer name, Milpharm Limited, along with a traceable batch number and expiry date.

Can people with severe lactose intolerance take Milpharm Modafinil?

Milpharm Modafinil tablets contain lactose monohydrate as an inactive binding excipient (approximately 113.5 mg per 100mg tablet). Patients with severe hereditary conditions such as total lactase deficiency, Lapp lactase deficiency, or glucose-galactose malabsorption should consult their prescribing physician before taking Milpharm formulations.

Can Provigil Be Used for Multiple Sclerosis (MS) Fatigue?

Modafinil induces the hepatic enzyme CYP3A4/5, which accelerates the breakdown of ethinylestradiol and progestogens. This significantly decreases the reliability of combined oral contraceptive pills, progestogen-only pills, patches, and implants. UK MHRA guidelines mandate using non-hormonal barrier methods or intrauterine devices (IUDs) during treatment and for two full months after discontinuing Milpharm Modafinil.

Is Milpharm Modafinil available on the NHS?

Yes. Milpharm Modafinil is widely distributed across NHS hospital trusts and community pharmacies within the UK. As a cost-effective generic formulation, it is commonly dispensed for licensed indications like narcolepsy and off-label under specialist shared-care agreements for Multiple Sclerosis (MS) fatigue.

Written By:

Matthew Young

Medical Writer at Modafinil UK

Hi, I’m Matthew Young, a medical writer and editor based in the United Kingdom. I’m currently researching modafinil medicines, including Provigil, Milpharm Modafinil, Teva Modafinil, Accord Healthcare Modafinil, Brown & Burk UK Modafinil, Generic Modafinil and other brands, with a focus on medicine identification, regulatory guidance, product quality, safe usage, patient safety, and so on. My work combines medical literature, manufacturer information, and UK healthcare guidance to produce accurate, evidence-based articles that are easy to understand.